Stem Cells Discovered in Fat May Treat Macular Degeneration, Retinitis Pigmentosa, Stargardt’s

adult fat stem cellsThe potential is great for these stem cells to aid in healing damaged and diseased tissues. Not to mention most adults wouldn’t mind giving up a little extra fat for something that could save lives.

Stem cells are valued tremendously for their ability to transform into any type of tissue. The capability of the cells to grow into anything from bone to nerve to heart translates to the conceivable treatment of countless diseases. Previous research has largely been Continue reading “Stem Cells Discovered in Fat May Treat Macular Degeneration, Retinitis Pigmentosa, Stargardt’s”

AMD Inhibited by Lutein, Carotenoids, and Zeaxanthin Antioxidants

amd blind braille bookNew evidence continues to support dietary lutein, carotenoids, zeaxanthin, and meso-zeaxanthin as a means of inhibiting development of age-related macular degeneration (AMD). AMD is the leading cause of loss of vision in Western people over age 55.

A study published in 2010, in Archives of Biochemistry and Biophysics by the Department of Ophthalmology and Visual Sciences at University of Utah, found that production of singlet oxygen in the human retinal pigment epithelium (RPE) and choroid is prevented or reduced by lutein, zeaxanthin, and meso-zeaxanthin, which act as Continue reading “AMD Inhibited by Lutein, Carotenoids, and Zeaxanthin Antioxidants”

Macular Degeneration Treatment Sought in Anti-Cholesterol Drops

macular degeneration treatment?A recent study linking cholesterol and macular degeneration may shed light on a highly significant problem caused by aging and potentially illuminates hope for a treatment or perhaps even a cure.

Macular degeneration is the leading cause in partial or complete blindness of adults over 60 in the United States. The disease targets the macula in the eyes which in large part is what enables us to perceive the fine detail that allows us do things like reading and driving.

A new study, published in the journal Cell Metabolism on April 2 2013, involved the study of macrophages from old mice and humans with macular degeneration. Macrophages, white blood cells that deconstruct cholesterol, have been found in higher than normal concentration in subjects with macular degeneration. In previous studies, this cellular build up has been shown Continue reading “Macular Degeneration Treatment Sought in Anti-Cholesterol Drops”

Eye’s Stem Cells May Provide Key to ARMD, Retinitis Pigmentosa, Stargardt’s Disease

researcherResearchers have found a layer of tissue in the eye that can self-renew and may provide cures in the future for retinal diseases such as Age-Related Macular Degeneration (ARMD), Stargardt’s disease, Best’s disease, and some types of retinitis pigmentosa. These eye diseases begin in the retinal pigment epithelium (RPE), which is a layer of eye tissue that supports the cells that make vision possible (photoreceptors). When the RPE degenerates, vision is compromised and can result in blindness.

Around ten percent of the cells in the RPE can renew themselves. In essence, they are dormant RPE stem cells. Cures for retinal diseases could lie in coaxing the dormant stem cells into becoming mature RPE cells. This could undo the damage from retinal diseases Continue reading “Eye’s Stem Cells May Provide Key to ARMD, Retinitis Pigmentosa, Stargardt’s Disease”

Squalamine Eye Drops Clinical Trial for Wet Macular Degeneration (ARMD)

Squalamine from shark liver or synthesizedResearchers are looking into squalamine eye drops as a treatment for wet (neovascular) Age-Related Macular Degeneration (ARMD). Their goal is evaluate the safety and effectiveness of squalamine lactate eye drops in improving wet AMD, the less-common forms of AMD.

ARMD is a degenerative eye disease that causes central vision loss. It progresses over time and can results in significant vision loss. The disease is prevalent in the aging. This will be a double-blind study with randomized assignment, which is considered to be a very strong research design. It also means Continue reading “Squalamine Eye Drops Clinical Trial for Wet Macular Degeneration (ARMD)”

Aspirin Associated with Wet Age-Related Macular Degeneration (ARMD)

age related macular degenerationA study involving more than 2000 participants in Australia has shown an association between regular aspirin use and wet age-related macular degeneration (ARMD). The prospective analysis study involved four examinations over 15 years (1992-1994 to 2007-2009). Subjects filled in a questionnaire at the beginning of the study that recorded aspirin usage, heart disease and risk factors for ARMD. A retinal photograph was taken at each examination to determine whether subjects had wet (neovascular) ARMD and dry (geographic atrophy) ARMD.

Of all the subjects, 10.8% of them used aspirin regularly. The study results showed that they were more likely to develop wet ARMD (9.3% in aspirin users versus 3.7% in non-aspirin users). Even after adjusting for age, gender, smoking, history of Continue reading “Aspirin Associated with Wet Age-Related Macular Degeneration (ARMD)”

Flavonoids in Deeply Colored Berries Protect People From Disease

blueberries and raspberries antioxidantsA fruit cup of mixed berries is a powerful snack: deeply colored fruits are filled with flavonoids and other antioxidants that help protect the body from disease. Antioxidants help prevent free-radical damage, which is believed to be responsible for the onset of eye diseases such as cataracts and macular degeneration.

The colored flavonoids found in berries are called “anthocyanins”. These water-soluble pigments make plants shades of red, purple and blue. Berries also contain flavonoids called “quercetin” and “apigenin”. In the field or in the wild, these flavonoids help protect the plant from pests and insects.

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Carnosic Acid from Rosemary Herb Protects the Eye

rosemary herb contains carnosic acid for eyesA chemical that occurs naturally in the common herb rosemary has been found to protect the eye from macular degeneration and other eye diseases. This study, published in Investigative Ophthalmology and Visual Science, is one of many recent investigations into the anti-inflammatory and antioxidant effects of the active ingredients in medicinal herbs. The compound in Rosemary is called “carnosic acid.”

Rosemary is a savory herb that adds flavor to a variety of recipes, including chicken, barbeques, salad dressing and tomato dishes. A member of the mint family, it is native to the Mediterranean region. Rosemarinus officinalis has evergreen, needle-like, fragrant leaves and tiny colorful flowers. It is a common decorative plant in gardens.

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Gestational Eye Development Requires Light

baby and fetal eye developmentThe developing pre-natal eye requires light that passes through the body and into the womb, according to recent animal research. Mice that had no access to light during pregnancy gave birth to offspring whose eyes were not developed correctly. This indicated that small amounts of light are necessary, during gestation, to control eye blood vessel growth.

This research is considered to be a breakthrough, and scientists were surprised because until now, maternal exposure to light during pregnancy was not considered relevant to fetal development.
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