The Food and Drug Administration (FDA) has recommended that the block-buster sleeping pill Ambien (zolpidem) dose be lowered, especially for women, due to negative side-effects. The drug stays in women’s system much longer than in men’s. Too many car accidents the day after taking Ambien have lead to the government agency to halve the recommended dose for women, and re-consider the dose for men.
Continue reading “Dose Size of Sleeping Pill Ambien Lowered Due to Negative Effects”
A significant study has found that the deleterious effects of traumatic brain injury in American football players can be mitigated using a natural regimen of weight loss (if needed), fish oil, vitamins, and brain-enhancing supplements including ginkgo biloba. The positive results could help reverse brain damage in contact sport athletes, alcohol and drug addicts, chronic traumatic encephalopathy (CTE) and people who have had brain damage from concussions.
You may have heard that medical marijuana is sometimes used by glaucoma patients. When most people in the United States think of marijuana, many different images, words, and opinions come to mind. Marijuana, or cannabis, is known for its psychoactive effects and medicinal properties caused by a chemical within the plant called tetrahydrocannabinol, also known as THC. Marijuana is most commonly recognized as a recreational drug and is subject to many legal restrictions ranging from its use, to possession of certain amounts of the plant product.
Continue reading “Medical Marijuana and Glaucoma: Does It Help?”
Everyone who suffers from migraine headaches wants to know how to prevent their next migraine. Recent strong research has resulted in guidelines for doctors to help prevent their patients’ future migraines, including the use of herbs, vitamins and minerals. The guidelines make recommendations for specific types of patients, such as patients with certain other conditions, obese patients, new migraine patients, and pregnant/lactating women.
This research, conducted by the Canadian Headache Society, reviewed a large body of double-blind studies according to standardized criteria. They also did a general literature review and got expert consensus for aspects of prophylactic (preventative) migraine therapies that did not have randomized clinical trials.
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As people age, eye diseases and conditions that commonly occur include macular degeneration, cataracts, vitreous tears/retinal tears and detachments, glaucoma, diabetic retinopathy, dry eyes, and eye floaters.
The question arises as to whether eye disease is inevitable with age. Will all older adults eventually have a “glint” in their eyes after cataracts surgery? More than 50% of people aged 75+ have glaucoma, cataracts, or macular degeneration. Can aging adults do anything to prevent, manage or slow down eye diseases associated with aging?
A large body of research is accumulating that shows the effects of regular eye exercises, good nutrition, and targeted supplementation on preventing and/or managing eye conditions. For instance, peer-reviewed research has shown that the risk of getting macular degeneration can be significantly reduced by taking fish oil and lutein on a daily basis. Vigorous exercise may reduce the incidence of glaucoma. And the effects of antioxidants on preventing cataract and macular degeneration have been the subject of significant research.
Drug maker GlaxoSmithKline has been found guilty of fraud in the way it reported research on, or marketed, on 3 of its medications in the largest settlement against a drug company in US history–$3 billion. The issues involved 10 drugs, and included marketing “off-label” use of the antidepressants Paxil and Wellbitrin and the asthma drug Advair, and not reporting all the safety data for the diabetes drug Avandia.
GlaxoSmithKline pleaded guilty and agreed to pay $3b total in both criminal fines and civil settlements with the federal and state governments. The fines will be paid next year.
In a press conference, Deputy US Attorney General James Cole said the settlement was “unprecedented in both size and scope.”
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A pilot study published in Phytotherapy Research compared curcumin – derived from natural turmeric – with the drug diclofenac for treating rheumatoid arthritis (RA). Natural curcumin actually reduced RA symptoms even better than the RA drug diclofenac: a 44% reduction in symptoms on the Disease Activity Score and the American College of Rheumatology criteria for reduction of swelling and tenderness of joins. Patients receiving diclofenac had a 42% reduction.
This is good news because curcumin has no known side-effects. Using anti-inflammatory medications over the long term sometimes has side effects that can result in stomach ulcers and damage to the kidneys. The extremely popular non-steroidal anti-inflammatory medication Vioxx (Rofecoxib – $2.5 billion in sales in 2003) was removed from the market in 2004 due to increased risk of heart attacks and stroke.
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Eye disorders related to statins are rare, occurring in about 0.1 percent of patients (0.5 to 2.5 percent when gemfibrozil, another type of cholesterol-lowering drug, is taken simultaneously) but had not been systematically reported prior to the study led by F.W. Fraunfelder, MD, of the Casey Eye Institute at Oregon Health and Science University. The research appears in the December issue of Ophthamology, the journal of the American Academy of Ophthamology.]
Fraunfelder’s group analyzed statin-associated reports of double vision (diplopia), drooping of the upper eyelid (ptosis), and loss of full range of motion of the eyes (ophthalmoplegia) in the databases of the National Registry of Drug-Induced Ocular Side Effects, the World Health Organization, and the Food and Drug Administration. Since statins were known to cause
skeletal muscle disorders in some patients, a similar affect was plausible in the eye muscles. The average patient age was 64.5 years, and the case reports included 143 males, 91 females, and 22 persons with gender unspecified. The average statin dose of patients who exhibited one or more eye disorder was within ranges recommended by drug manufacturers, and the average
time from beginning of therapy to developing an adverse drug reaction (ADR) was 8.3 months. There were 23 cases of loss of eye range of motion; 8 cases of ptosis, and 18 cases of ptosis in conjunction with double vision; disorders in all patients apparently resolved completely when statins were discontinued. From the ADR reports, the researchers could not determine
precisely which eye muscles were involved, or time needed to full recovery after statin discontinuation, for individual cases.
Learn more about drugs that can harm vision.